Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Going off plaquenil Chloroquine indication Antimalarial Drugs. If your plans include travel to southern Africa or another part of the world where malaria is common, you might need medicine to protect yourself against the mosquito-borne disease. But be aware. If you have psoriasis, chloroquine Aralen and hydroxychloroquine Plaquenil can cause problems. Acute generalised exanthematous pustulosis AGEP is a severe drug-induced eruption that closely resembles generalised pustular psoriasis. Palmoplantar pustulosis can also be drug-induced, often by tumour necrosis factor inhibitors. Although closely related, palmoplantar pustulosis is no longer classified as a type of psoriasis. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil induced psoriasis Hydroxychloroquine in Psoriasis Is it Really Harmful., Drug-induced psoriasis DermNet NZ Hydroxychloroquine medicationHydroxychloroquine effects on blood sugarHydroxychloroquine keratopathyPlaquenil cumulative dose toxicity Sometimes used to treat lupus and rheumatoid arthritis, Atabrine quinacrine, Aralen Phosphate chloroquine, and Plaquenil hydroxychloroquine may cause a flare of psoriasis, usually two to. Medications That Can Trigger Psoriasis - Psoriasis Center.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Increased cutaneous reactions to hydroxychloroquine.. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. A variety of pharmacologic agents have been known to induce pustular psoriasis. We describe a patient with a positive personal and family history of psoriasis who developed an extensive annular pustular eruption 3 weeks after starting hydroxychloroquine Plaquenil for arthritis.