Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine plaque psoriasis Hydroxychloroquine plaquenil for malaria protection peru Chloroquine sulphate bp 400mg Hyperpigmentation plaquenil The main outcomes were toxicity as determined by characteristic visual field loss or retinal thinning and photoreceptor damage. They also examined risk factors and prevalence. The study findings revealed that when hydroxychloroquine was used at doses 5mg /kg, the risk of retinopathy was 1% in the first 5 yrs. 2% in 10 yrs. 20 % after 20 yrs. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Patients often ask if their medications affect the risk of vision loss from age-related macular degeneration AMD. One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Macular thinning and plaquenil Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS, Hydroxychloroquine Plaquenil Hydroxychloroquine sulphate tablets in indiaHydroxychloroquine 200 mg overdoseIs hydroxychloroquine an immunosuppressant drug Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Taking Plaquenil for Rheumatoid Arthritis. Prescription Medications That Can Affect Age-Related Macular.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. The central macular area was 2800 µm in diameter approximately 10 degrees, centered at the foveal center. The perifoveal area was defined as a 1200-µm-width ring surrounding the central macular area. The overall macular area was 5200 µm in diameter, centered at the foveal center. The retinal ganglion cells are densest in the macula and form a stratified multi-cellular layer within the central 6 degrees of visual field. Therefore, loss of axons and the corresponding soma in this location is likely to cause a thinning of the retinal ganglion cell layer. Mar 17, 2017 Plaquenil is known to show retinal toxicity which can effect the vision and it is imperative to be able to spot any changes and to contact the patient's rheumatologist to notify them about the changes. The presentation goes over how to spot and what testing to perform to make sure there is no retinal toxicity.