Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil low stool siga Can hydroxychloroquine cause weight gain hair loss Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Other rare side effects include changes in skin pigmentation and cardiomyopathy diseases of the heart muscle. The future. Hydroxychloroquine was previously prescribed only for people whose lupus disease activity was mild in its course; if the lupus became active, steroids or immunosuppressants would be prescribed instead. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye;. RARE side effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Lupus and plaquenil side effects Hydroxychloroquine Plaquenil Success, Reviews and Side Effects, Drug spotlight on hydroxychloroquine Lupus Foundation of. Define hydroxychloroquine What are the side effects of hydroxychloroquine Plaquenil? Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Common and Rare Side Effects for Plaquenil Oral. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Side effects associated with Plaquenil are placed in three categories common, less common, and rare. If you have any of the following effects and they persist or worsen, notify your doctor or pharmacist promptly. It is important to remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Although they are uncommon, Plaquenil has side effects that may affect your eyes. With all of the physical and emotional complications that lupus can cause, it’s easy to overlook symptoms that seem minor at first. But take this advice Don’t ignore changes in vision. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage.