Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take chloroquine with all of your drugs and health problems. Dr reddy's laboratories hydroxychloroquine Cat's claw and hydroxychloroquine Pharmacology of chloroquine Chloroquine diphosphate, apoptosis and autophagy inhibitor CAS 50-63-5, with 98% purity. Water soluble compound. Join researchers using our high quality biochemicals. Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion. Chloroquine phosphate 50-63-5 is an antimalarial drug. Inhibits autophagy in a variety of cell lines 1. Induces cell death in breast cancer cell lines and displays antitumor and antimetastatic activity in mouse models of breast cancer 2. Eliminates cancer stem cells via deregulation of Jak2 and DNMT1 3. For all uses of chloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Chloroquine diphosphate autophagy APExBIO - Chloroquine diphosphateAntimalarial drugCAS# 50-63-5, Chloroquine - Wikipedia Does plaquenil effect celiacPlaquenil caterats Search results for Chloroquine at Sigma-Aldrich. Summary This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Chloroquine Sigma-Aldrich. Chloroquine phosphate autophagy inhibitor. Autophagy Inhibitors - Autophagy Sigma-Aldrich. Mar 16, 2017 Classic autophagy inhibitors 3-methyladenine 3-MA and chloroquine CQ can inhibit lung and colon cancers and thus have potential for tumor treatment 16–18. The small alkaline molecule CQ can accumulate in lysosomes, which will change the lysosome acidity, causing reduced hydrolysis. Product name Chloroquine diphosphate, apoptosis and autophagy inhibitor. Description Antimalarial; apoptosis and autophagy inhibitor. Biological description Antimalarial agent. Inhibits tumor cell growth and metastasis and induces apoptosis in vitro. Chloroquine is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors TLRs.