One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Aralen patient teaching Plaquenil cost at walmart Optical Coherence Tomography, or OCT, is advanced technology used for retinal imaging and analysis. This technology provides highly detailed images of the retina as well as the optic nerve. These cross-sectional images are viewable in 2D and 3D, allowing for topographical mapping of the eye including macular thickness. This case demonstrates that the findings of HCQ retinopathy on en face structural OCT are analogous to those identified by current imaging modalities used for the screening and diagnosis of HCQ toxicity. En face structural OCT may be useful in the detection of HCQ-induced retinal toxicity. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Oct en face retina mesaurements plaquenil Chloroquine And Hydroxychloroquine Toxicity - StatPearls., Use of En Face Optical Coherence Tomography in a Case of. Chloroquine lysosomal membrane permeabilizationIs chloroquine a quinolineChloroquine tablets brand india H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. The most common side effect associated with its use is retinal toxicity, which may be irreversible. Retinal Physician - Hydroxychloroquine Maculopathy An.. Plaquenil Uses, Dosage & Side Effects -. Pause the Plaquenil?. OCT, especially high-resolution spectral-domain SD-OCT, permits the visualization of all retinal layers, as well as the vitreous and the choroid. Localization of an abnormal finding to a specific layer of the retina often leads to a diagnosis that would not be otherwise possible. Hydroxychloroquine HCQ; Plaquenil retinopathy ie, HCQ toxicity is a severe complication associated with HCQ intake that can cause irreversible vision loss.1–3 Early detection of retinal toxicity is crucial since vision loss is usually permanent and cellular damage may progress despite discontinuation of treatment.2 3 Although no ideal single test exists for identification of early toxicity, spectral-domain optical coherence tomography SD-OCT plays a critical role in identifying. Screening for Plaquenil Toxicity • SD-OCT can show localized thinning of the. image 2D en face representations of common retinal layers/disorders Allows you to isolate and visualize a layers of the retina The thickness and placement. measure the affected area.