They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Reviews on plaquenil for rheumatoid arthritis Do hydroxychloroquine get you high For some people with very mild lupus, NSAIDs alone are enough to control symptoms. Antimalarial drugs. Hydroxychloroquine Plaquenil is used to treat malaria, and researchers have found that this drug also helps with lupus flares. These drugs work well with mild to moderate cases of lupus. Apr 01, 2013 Methotrexate does suppress the immune system, but serious infections with methotrexate are not common. Your rheumatologist will monitor you closely for any side effects associated with methotrexate such as liver test abnormalities, pneumonitis, or infections. Almost all autoimmune diseases require the immune system be suppressed. Feb 19, 2020 Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. Can plaquenil lower your immune system Plaquenil and immune system Lupus Forums at The Lupus Site, Methotrexate Does it weaken my immune system? Chloroquine diphosphate and phosphate I see so much info on the net where some says that Plaquenil has very mild effect on immune system except for eye issues --- Other info says it is an immunosuppressant. Must I choose "my poison" figuratively speaking not literally! Plaquenil and its affect on the immune system DailyStrength. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Inflammatory Osteoarthritis And Plaquenil. If there is a lot of joint pain, as in RA, there is generally reduced mobility and stiffness in the affected joints. Plaquenil and other anti-malarials such as hydroxychloroquine is thought to act by interfering with the production and release of blood cells that are involved in the body's immune defence system. We know about this with our lupus. Aug 02, 2010 Plaquenil works by suppressing the immune system. Unfortunately you can't tell it to attack just the germs so you suppress all of its function to spare your healthy tissue- in your husband's case, his eyes, mouth, throat. NOTE Plaquinil and hydroxychloroquine are essentially the same drug. The same effects should be expected from both drugs. 2. No, his immune system should not be forever compromised. Jun 13, 2019 Plaquenil lowers your immune system’s ability to cause inflammation. This can help control symptoms like rashes, skin and mouth sores and joint pain. Plaquenil and your eyes A rare side effect of Plaquenil is damage to the eye's retina.