Symptoms — which include pain and tingly, creepy-crawly sensations — usually strike at night or when you’re relaxing, so sleep problems are one of the chief complaints in people with restless legs syndrome, or RLS. Although RLS is a neurological problem, certain environmental and external factors have been known to exacerbate symptoms. Chloroquine vs hydroxychloroquine Benadryl and hydroxychloroquine Hydroxychloroquine - as a side affect has anyone had it cause restless body syndrome or restless leg Asked by jonzvet Updated 4 December 2015 Topics sjogren's syndrome, restless legs syndrome, hydroxychloroquine, side effect, syndrome Lifestyle choices, medications, or even other medical conditions can make restless legs symptoms worse. Learn about common restless legs triggers to avoid. Restless legs syndrome, or RLS, is the term given to a medical condition whereby people have crawly, tingly or pulling sensations in their legs, or an overwhelming urge to move their legs. The sensations usually occur during periods of inactivity, such as when a person has been sitting at a desk for a while or at night after lying down. Medications may be most effective for severe RLS, but identifying and avoiding things that aggravate your symptoms can also help, especially in mild or moderate cases. Avoiding these common restless legs triggers may help calm your jittery limbs so you can get the rest you need. Can plaquenil cause restless leg syndrome Restless legs DailyStrength, Triggers That Make Restless Legs Worse Everyday Health Chloroquine Restless leg syndrome RLS is a medical condition in which there are strong urges to move the legs along with unpleasant symptoms of crawling, tingling, burning, and aching, and leg pain or cramps. The main cause of restless leg syndrome is a problem using iron in the brain or a lack of iron. Restless Leg Syndrome Treatment, Medication, Causes, Symptoms. Drugs That Cause Restless Leg Syndrome Healthfully. The 11 Best Treatments for Restless Legs Syndrome. Of this group, 25 to 40% report sleep disturbances related to RA, says the sleep specialist at St. Luke’s Hospital in Bethlehem, Pennsylvania. The rest, he says, may have a sleep disorder in addition to RA, such as sleep apnea or restless legs syndrome. Can Plaquenil cause RLS? Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. In most of these discussions patients report that Plaquenil doesn't cause RLS. Don't want to become dependent. The restless leg is under control most of the time. I am on mirapex before bed and a neupro. If you've got restless legs syndrome RLS, your daily habits can make a difference to your condition. Revamping your diet, exercise, and medications is just the beginning of what you can do to.