While the mechanism is poorly understood, pregnant women have a reduced immune response and therefore less effectively clear malaria infections. In addition, malaria parasites sequester and replicate in the placenta. Hydroxychloroquine blood tests Hydroxychloroquine sulfate 200 mg tab side effects What does hydroxychloroquine do for ra Hydroxychloroquine at night Chloroquine crosses the placenta, but the potential damage to the mother from malaria is greater than the drug's risk to the fetus. Weekly prophylactic doses appear to have minimal adverse effects when administered during pregnancy. Usual Adult Dose for Malaria Prophylaxis. 500 mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart. Chloroquine phosphate tablets should not be used in these conditions unless the benefit to the patient outweighs the potential risks. Usage in Pregnancy Usage of Chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus. Malaria infection during pregnancy can lead to miscarriage, premature delivery, low birth weight, congenital infection, and/or perinatal death. Pregnant women are three times more likely to develop severe disease than non-pregnant women acquiring infections from the same area. Chloroquine dose during pregnancy Chloroquine - an overview ScienceDirect Topics, Chloroquine Dosage Guide with Precautions - Plaquenil and extreme fatiguePlaquenil retinal screening guidelines afters stoppingAllergy signs to hydroxychloroquineSide effects coming off plaquenil Pregnancy and Chloroquine According to the Centers for Disease Control and Prevention CDC, chloroquine is considered safe to use during pregnancy. Tell your doctor if you're pregnant or might. Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs. Chloroquine - FDA prescribing information, side effects and uses. Chloroquine Oral Uses, Side Effects, Interactions, Pictures.. Ten women who were taking oral chloroquine 300 mg/week of chloroquine during pregnancy were changed to a dose of 100 mg/day for the last 10 days of pregnancy and first 10 days postpartum. Milk samples were taken daily for 3 days during the first 10 days postpartum at the end of nursing time after dose unspecified. Pregnancy. There are no adequate and well-controlled studies evaluating the safety and efficacy of chloroquine in pregnant women; usage during pregnancy should be avoided except in prophylaxis or treatment of malaria when benefit outweighs potential risk to fetus. Lactation It appears to be safe for use during pregnancy. Chloroquine is a member of the drug class 4-aminoquinoline. It works against the asexual form of malaria inside the red blood cell. Chloroquine was discovered in 1934 by Hans Andersag.