Head over to this page: https://messageboards.webmd.com/health-conditions/f/lupus/2. Choose the tag from the drop-down menu that clicks most with you (and add it to any posts you create so others can easily find and sort through posts)3. Email us anytime at [email protected] I was dx in August with Lupus and my Rheumy said she was afraid to start me on Plaquenil since I had a bad reaction to a Sulfa antibiotic I took and the same reaction when a Dr gave me Lasix. I think I'm going to tell my Rheumy that I at least want to try Plaquenil and take the risk (I only got a really red rash that looked like measles when I had the reaction).thanks, Robin I have a sulfa allergy, and have taken Plaquenil for 4 years without any adverse effects. I read that the sulfa in Plaquenil is different from those in antibiotics and most people with Lupus have an allergy to Sulfa but can take Plaquenil without any problems. I can say, however, that I have not had any cross allergic reaction to other drugs sometimes associated with sulfa allergies. Easily bruising side effect of plaquenil Plaquenil for autoimmune disorders Plaquenil skin pigmentation Someone who has a sulfa allergy can react to some medications that contain sulfa. Sulfonamide antibiotics that can cause a reaction. Antibiotics containing chemicals called sulfonamides can trigger a reaction if you have a sulfa allergy. These antibiotics include combination drugs I am allergic to sulfates. Is all Plaquenil medicine bound with sulfates? no, just sulfates. I only take bystolic, no - Answered by a verified Pharmacist I am allergic to sulfa i.e wheezing after sulfa based antibiotics, but have never had problems with Plaquenil. It's been such a helpful drug for the fatigue that I'm so glad that it's never presented any problems. I don't take certain NSAIDs e.g. Celebrex, but can tolerate most of them. Rashes are certainly a lot less severe than respiratory reactions. Whether you try Plaquenil or not is ultimately up to you and your doctor, but a lot will depend on the type and severity of reactions that you've had. Can i take plaquenil if allergic to sulfa If you are allergic to sulfa drugs does this mean you can., I am allergic to sulfates. Is all Plaquenil medicine bound. Plaquenil alcohol consumption Often people are allergic to sulfa drugs and sulfites. Therefore may think that it is necessary for them to avoid sulfates and sulfur, as well. In this article I will explain to you the differences between these four substances and the allergic reactions to be aware of. Sulfa Drugs Sulfonamides Are You Allergic to Sulfur? Allergies to Sulfur, Sulfites.. Sulfa allergy and anti-malarials?" Lupus Community.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. If you definitely cannot take the plaquenil, then you should speak with your rheumy about starting may make you start to feel better. There are other anti-malaria drugs on the market that your rheumy can put you on instead of the plaquenil. But, make sure the he/she is convinced that you are actually allergic to the plaquenil. Dec 22, 2017 Sulfa allergy can result in serious complications, including anaphylaxis and Stevens-Johnson syndrome. Anaphylaxis. Anaphylaxis is a severe and potentially life-threatening type of allergic reaction. Plaquenil isn't a 'sulfa' drug which means a certain sort of antibiotic, the sulfonamides. Plenty of people who are allergic to those sulfa drugs take Plaquenil without any problem. This sounds all very odd to me!