Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine drug name Does hydroxychloroquine cause bone grafts to fail Hydroxychloroquine side effects fluid retention It seems like ever since I went on hydroxychloroquine 3 months ago I’ve had itching. They upped my dose to 400mg a couple of weeks ago and now I’m experiencing intense itching. To the point where my skin almost has a stinging sensation. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil itching side effects Hydroxychloroquine Sulfate Rash Reports - DrugInformer, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Plaquenil radiation therapyCan plaquenil cause extreme fatigueHydroxychloroquine & methotrexate If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Plaquenil Side Effects on Your Eyes and Vision. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Itching in Plaquenil how severe and when it was recovered.. Plaquenil should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. Dermatologic Effects Dermatologic reactions to Plaquenil may occur and, therefore, proper care should be exercised when it is administered to any patient receiving a drug with a significant tendency to produce dermatitis. Hi, I started taking Plaquenil on June 24th and for the last four or 5 days have had horrible itching. No rash just all over itching. My Rhuemy told me to stop taking it until all itching symptoms were gone, then wait another week and start up again with 1 pill 200mg a day instead of 2. The crazy thing about this itching is that this is the 3rd attempt back on the plaquenil and with the 1st two tries I had no itching but different side effects that made me discontinue it. The 1st time I was on it brand name 400 mg. for 8 months and had to d/c due to terrible intestinal cramping and tinnitus.