I would appreciate feedback on the reasoning outlined below. I have convinced myself that it makes sense, but am looking for independent feedback and have been struggling to get it. Plaquenil drug eruption Chloroquine phosphate leth Side affects hydroxychloroquine Bulleye chloroquin retinopathy TreatmentResearchPharmacologySymptomsRisksInteractionsAdministrationResults A study of about 200 patients with a history of hydroxychloroquine retinopathy, including 36 Asian patients, found that the pericentral pattern occurred in half the Asian patients but only 2% of the white patients. 31 The mechanism for this finding is unclear, but because pericentral retinopathy spares the macula, it can be missed using standard screening methods. Mechanism of Action of Hydroxychloroquine as an Antirheumatic Drug By Robert I. Fox The antimalarial agents chloroquine and hydroxychloroquine have been used widely for the treatment of rheumatoid arthritis and systemic lupus erythematosus. These compounds lead to improvement of clinical and laboratory parameters. , etc.), or provide argument why this is a dumb idea. I would greatly appreciate it if someone could knit-pick this with a fine tooth comb and try and find some mistake I've made (off by a order of magnitude? Mechanism of action hydroxychloroquine Hydroxychloroquine Plaquenil Side Effects & Dosage for., Hydroxychloroquine An old drug with new relevance. What is aralen used forDoes hydroxychloroquin cause low wbc1989 honduras chloroquine Disease-modifying antirheumatic drugs DMARDs are a group of medications commonly used in people with rheumatoid arthritis. Some of these drugs are also used in treating other conditions such as ankylosing spondylitis, psoriatic arthritis, and systemic lupus erythematosus. They work to decrease pain and inflammation. UpToDate. Mechanism of action of hydroxychloroquine as an antirheumatic.. Hydroxychloroquine Sulfate Drug Information, Professional. Hydroxychloroquine oral tablet is used for short-term treatment of malaria, but it may be used for long-term treatment of lupus or rheumatoid arthritis. Hydroxychloroquine comes with risks if you. The efficacy of antimalarials, especially hydroxychloroquine HCQ, in preventing systemic lupus erythematosus SLE flares is well demonstrated. However, many studies show that the percentage of SLE patients treated with HCQ remains low. Cytochrome P450 enzymes converts hydroxychloroquine into its active metabolite, desethyl hydroxychloroquine.6 The onset of action may take up to 4–6 weeks post-commencement of therapy, and it may take 3–6 months to achieve maximal clinical efﬁcacy. The recommended maintenance dose of hydroxychloroquine is 200–400 mg daily.