Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Plaquenil en español Foods to avoid while taking plaquenil Hydroxychloroquine mechanism of action Chloroquine phosphate suspension ip in hindi Thereafter, the AAO states annual screening can be deferred until year 5 on the medication but should start sooner if the patient is at a higher risk for toxicity. The guidelines recommend 1 an automated visual field as well as a 2 spectral-domain optical coherence tomography SD OCT. The latest screening guidelines were published in 2016 by the American Academy of Ophthalmology Table 1. The most important risk factors are dosage and duration of use. Dosage greater than 5.0mg/kg over five years dramatically increases the risk of retinal toxicity, and high doses can be exceedingly dangerous. In 2002, the American Academy of Ophthalmology AAO established ocular examination guidelines for screening patients on Plaquenil therapy. Testing included a comprehensive eye exam that consisted of an assessment of the posterior segment with careful evaluation of associated macular changes or signs of retinal disease. 4 Baseline fundus. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Plaquenil guidelines aao 2016 Detection of Hydroxychloroquine toxicity based on AAO 2016., How to Succeed in Plaquenil Screenings What is a normal dose of plaquenilH-chloroquine side effects Impact of the revised American Academy of Ophthalmology guidelines regarding hydroxychloroquine screening on actual practice. Easterbrook M, et al. Recommendations on screening for chloroquine and hydroxychloroquine retinopathy a report by the American Academy of Ophthalmology. 186-1394 2016 by the American Academy of. Recommendations on Screening for Chloroquine and.. New Plaquenil Guidelines -. New Guidelines on Hydroxychloroquine Dosage - Where Are We.. The recommended dose was calculated based on the American Academy of Ophthalmology AAO 2016 guidelines recommendation of not more than 5 mg/kg/day actual body weight. Patients were also asked about unwanted symptoms they had reported to their doctor, gastrointestinal GI effects they had experienced and aspects affecting their adherence. AAO revised guidelines. The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight. The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. Hydroxychloroquine And Chloroquine Screening 2016 AAO Recommendations The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1.