It is bioactivated hepatically to its primary metabolite, N-desethylamodiaquine, by the cytochrome p450 enzyme CYP2C8. Among amodiaquine users, several rare but serious side effects have been reported and linked to variants in the CYP2C8 alleles. Plaquenil sudden tightness neck pain Plaquenil for sjogren's reviews How long before itching stop after stopping plaquenil Unless otherwise noted, the contents of the FDA website gov, both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Structure, properties, spectra, suppliers and links for Chloroquine Phosphate, 1446-17-9. IUPAC name RS-N'- 7-chloroquinolin-4. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. People who are poor metabolizers of amodiaquine display lower treatment efficacy against malaria, as well as increased toxicity. CYP2C8*1 is characterized as the wild-type allele, which shows an acceptable safety profile, while CYP2C8*2, *3 and *4 all show a range of "poor metabolizer" phenotypes. Iupac name of chloroquine Hydroxychloroquine CHEBI5801, Chloroquine Phosphate C18H29ClN3O4P ChemSpider Levaquin interactions with plaquenilSide effects of hydroxychloroquine weight gain Name; Formula; IUPAC identifier; CAS number; More options; NIST Data. IUPAC Standard InChIKey WHTVZRBIWZFKQO-UHFFFAOYSA-N; CAS Registry Number 54-05-7; Chemical structure This structure is also available as a 2d Mol file;. Capquin; Cloroquine; Ronaquine; +/--Chloroquine. Chloroquine - NIST. Chloroquine - Wikipedia. Chloroquine - wikidoc. Chloroquine Sulfate is the sulfate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that. Chloroquine CAS NO.54-05-7 has long been used in the treatment or prevention of malaria. After the malaria parasite Plasmodium falciparum started to develop widespread resistance to chloroquine, new potential utilisations of this cheap and widely available drug have been investigated. Structure, properties, spectra, suppliers and links for Chloroquine diphosphate, 50-63-5, Chloroquine Phosphate.