Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil dosage for discoid lupus Replacement for hydroxychloroquine Neutropenia is a blood disorder characterized by a decreased number of white blood cells in the blood. Neutropenia tends to affect about 18 percent of persons taking Valtrex. This often results in a weakened immune system, making the patients more likely to acquire infection and creating a longer wound healing time. Primary autoimmune neutropenia. The AINs are classified as primary i.e. not associated with other detectable pathology or secondary, in cases in which there is another pathology, usually rheumatological particularly Felty's syndrome and systemic lupus erythematosus SLE or haematological large granular lymphocyte LGL syndrome. The results of their study, however, suggested an autoimmune mechanism for neutropenia in patients with SLE.9. Rustagi et al,11 in a study of 18 patients with SLE, suggested complement-activating antineutrophil IgG autoantibodies existed in SLE and their presence correlated with neutropenia. The neutrophil-binding IgG was 2–3 times higher. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil autoimmune neutropenia Hydroxychloroquine Plaquenil, Primary and secondary autoimmune neutropenia Plaquenil which companySynthesis of chloroquine pdfAralen artritis Autoimmune neutropenia, caused by neutrophil-specific autoantibodies is a common phenomenon in autoimmune disorders such as Felty's syndrome and systemic lupus erythematosus. Felty's syndrome is associated with neutropenia and splenomegaly in seropositive rheumatoid arthritis which can be severe and with recurrent bacterial infections. Management of autoimmune neutropenia in Felty's syndrome.. Haematological manifestations of lupus Lupus Science.. Hematological Disorders in Patients with Systemic Lupus.. Bel neutropenia low white cell count can be an autoimmune condition in and of itself. Those of use with AIs often develop several and gain more over time. Neutropenia is something to be concerned about as low counts leave you very vulnerable to infection. I know because I have neutropenia and my hematologist tracks my neutrophils carefully. Consumer information about the medication HYDROXYCHLOROQUINE - ORAL Plaquenil, includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug HYDROXYCHLOROQUINE - ORAL. People can have neutropenia without an increased risk of infection. This is known as benign neutropenia. Causes shown here are commonly associated with this symptom.