How chloroquine causes itch

Discussion in 'Hydroxychloroquine 200 Mg Tab' started by dreamhouse, 08-Mar-2020.

  1. edisson Moderator

    How chloroquine causes itch


    Itch has many similarities to pain, and while both are unpleasant sensory experiences, their behavioral response patterns are different. Pain creates a withdrawal reflex, whereas itch leads to a scratch reflex.

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    Effects of chloroquine? Chloroquine is a relatively well-tolerated. medicine. The most common adverse reactions reported are stomach pain, nausea, vomiting, and headache. These side effects can often be lessened by taking chloroquine with food. Chloroquine may also cause itching in some people. All medicines may have some side effects. Lead researcher Diana Bautista collected a variety of substances that cause the itch reflex, including a plant called cowhage and the drug chloroquine, which often causes a persistent, all-over itch. The itch produced by chloroquine is so common that in some African countries 70 percent of the population has been affected by it. Itching, also known as ‘pruritus’ in the medical world, can be more than a small annoyance. It can cause a lot of discomfort and may even become a distraction. When is itching serious and how.

    Pain and itch have very different behavioral response patterns. Unmyelinated nerve fibers for itch and pain both originate in the skin; however, information for them is conveyed centrally in two distinct systems that both use the same nerve bundle and spinothalamic tract.

    How chloroquine causes itch

    Chloroquine and hydroxychloroquine difference – Pro Laptop., Study suggests connection between itch and pain symptoms

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  7. PRURITUS or itch is a cutaneous sensation that leads to body scratching. Chloroquine is used both as an antimalarial drug and in the treatment of rheumatological disorders, such as rheumatoid arthritis and systemic lupus erythematosus.

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    Dec 25, 2009 Using the itch-inducing compound chloroquine, an antimalarial drug, the team identified that a family of proteins called Mrgprs, found only in a rare subset of nerve cells, functions as itch. A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided.

     
  8. maxp New Member

    Background: The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Recommendations on Screening for Chloroquine and Hydroxychloroquine. The Ultimate Guide to Optometry Billing and Coding. Multimodal Imaging in Plaquenil Toxicity
     
  9. kazZzantip Guest

    Doxycycline instead of Malarone for Malaria. - Fodor's Travel Talk Forums Africa & the Middle East - Doxycycline instead of Malarone for Malaria. - I was given a prescription of Doxycycline since I'll be visiting a malaria area in Sabi Sabi. Others I know seem to take.

    Doxycycline vs Malarone - Which Malaria Medication Is Right For Me?
     
  10. drum XenForo Moderator

    Chloroquine - Wikipedia Chloroquine enters the red blood cell, inhibiting the parasite cell and digestive vacuole by simple diffusion. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion.

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