Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Chloroquine and diazepam Chloroquin doses Chloroquine ppt Clinical practice guidelines recommend use of combination DMARDs such as hydroxychloroquine plus methotrexate for patients with a disease duration less than 6 months and moderate disease activity and poor prognostic features and is an option for high disease activity and poor prognostic features. Summary Drug interactions are reported among people who take Methotrexate and Plaquenil together. This study is created by eHealthMe based on reports of 23,242 people who take Methotrexate and Plaquenil from Food and Drug Administration FDA, and is updated regularly. Elevated levels of aminotransferases were more common in patients receiving methotrexate plus leflunomide, as were mild leucopenias and neutropenias. A 24-week open label extension converted those patients initially randomized to the methotrexate-placebo combination to methotrexate- leflunomide at 10-20 mg/day. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Combination methotrexate and plaquenil Which would you pick and why? - Plaquenil or Methotrexate, Methotrexate and Plaquenil drug interactions - eHealthMe Hydroxychloroquine histaminePlaquenil eye exam standard of careWhat are the side effects of hydroxychloroquine 200 mgWhat happens if you stop taking your plaquenilHydroxychloroquine rxnorm code Hydroxychloroquine may be used as part of a combination therapy. That means you may need to take it with other drugs. Taking methotrexate with hydroxychloroquine has not been studied. It may. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Combination Therapy for Rheumatoid Arthritis Methotrexate.. Combinations of conventional & biologic DMARDs. Original Article from The New England Journal of Medicine — Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications Dec 15, 2010 hello hope everyone is well just a quick question, i have been on methotrexate for 2 months increasing from 7.5 to 15 and now to 25mg.weekly now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects.