DLE is more common and more severe in smokers compared to non-smokers. Smoking also reduces the effectiveness of antimalarials and other therapies. Medicine for lupus plaquenil Maker of plaquenil Discoid lupus is a chronic autoimmune disease that causes a severe rash on the skin. It gets its name from the coin-shaped lesions it produces. Medications commonly used to treat malaria, such as hydroxychloroquine Plaquenil, affect the immune system and can help decrease the risk of lupus flares. Side effects can include stomach upset and, very rarely, damage to the retina of the eye. Regular eye exams are recommended when taking these medications. Learn all you can about lupus. Background. Hydroxychloroquine is widely used for the treatment of cutaneous lupus erythematosus CLE. Although new recommendations exist for hydroxychloroquine dosing, there is still uncertainty about the dosage that will elicit a satisfactory response in CLE while limiting adverse effects, specifically retinopathy. Between 5% and 25% of patients with DLE develop SLE, in which there may be other forms of cutaneous lupus, and other organs may develop the disease. Most patients with DLE just have skin involvement (cutaneous LE). Plaquenil for discoid lupus Stopping Plaquenil - General Discussion - Life With Lupus, Lupus - Diagnosis and treatment - Mayo Clinic Plaquenil medication guide I was diagnosed with Discoid lupus in 2009 and I began using Plaquenil once I stopped breastfeeding. Initially, the only difference I noticed was my hair stopped falling out. After taking Plaquenil for a less than a year my face and neck started turning black. My dermatologist is convinced that Plaquenil is the culprit and just recently. Plaquenil User Reviews for Systemic Lupus. -. An update on the use of hydroxychloroquine in cutaneous.. Drug spotlight on hydroxychloroquine Lupus Foundation of.. What is discoid lupus erythematosus. Lupus erythematosus LE is a group of diverse, persistent inflammatory autoimmune diseases and often affects the skin. Discoid lupus erythematosus DLE is the most common chronic form of cutaneous is characterised by persistent scaly, disk-like plaques on scalp, face and ears that may cause pigmentary changes, scarring and hair loss. Plaquenil Hydroxychloroquine may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Lupus Erythematosus. PLAQUENIL is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. Hydroxychloroquine and chloroquine phosphate have shown beneficial effects in treating discoid lupus erythematosus DLE. Additionally, The antimalarial drugs may prevent the development of systemic lupus erythematosus SLE in patients with DLE, and they might decrease the risk of cardiovascular disease.