It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. High triglycerides and plaquenil Solubility of chloroquine in water If OVERDOSE is suspected If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Hydroxychloroquine? Store at room temperature. Protect from light. Store in a dry place. The side effect that is of greatest concern is retinal toxicity. Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy. Hydroxychloroquine should be discontinued if ocular toxicity is suspected and patient should be closely observed given that retinal changes and visual disturbances may progress even after cessation of therapy. Hepatic disease or alcoholism This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Hydroxychloroquine overdose Plaquenil Hydroxychloroquine Side effects, Images, Uses., The Risk of Retinal Toxicity with Plaquenil How to wean off plaquenil This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Hydroxychloroquine-Induced Retinal Toxicity - American.. Plaquenil hydroxychloroquine sulfate dosing, indications.. Drug spotlight on hydroxychloroquine Lupus Foundation of.. It is available in 200 mg tablets of hydroxychloroquine phosphate each containing 155 mg of hydroxychloroquine. 1 Although commonly used in the treatment of rheumatologic diseases, it is a rare source of overdose in the United States. However, life-threatening symptoms can occur within an hour of ingestion. Children can be especially sensitive to an overdose, so keep the medication out of the reach of children. Children should not take hydroxychloroquine for long-term therapy. Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to hydroxychloroquine. An overdose of hydroxychloroquine can be fatal, especially in children. Take hydroxychloroquine for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared.