Regardless of the problem, we'd like to help you find what you're looking for. Sjogren's (SHOW-grins) syndrome is a disorder of your immune system identified by its two most common symptoms — dry eyes and a dry mouth. Do you have to take methotrexate and plaquenil together Chloroquine dose for lupus However rheumy says plaquenil does not target the specific symptoms of dry eyes and dry mouth. She is right. I treat my dry eyes with restasis drops and the dry mouth comes and goes. Yeast infections in the mouth should be treated with antifungal medications. Treat systemwide symptoms. Hydroxychloroquine Plaquenil, a drug designed to treat malaria, is often helpful in treating Sjogren's syndrome. Drugs that suppress the immune system, such as methotrexate Trexall, also might be prescribed. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased tears and saliva. Your immune system mistakenly attacks your body's own cells and tissues. The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. Plaquenil and dry mouth Ask the Expert Plaquenil and Sjögren’s, Sjogren's syndrome - Diagnosis and treatment - Mayo Clinic Plaquenil-tablets usesDrug warnings for plaquenilDoes hydroxychloroquine cause eye problems Dry eyes. Your eyes might burn, itch or feel gritty — as if there's sand in them. Dry mouth. Your mouth might feel like it's full of cotton, making it difficult to swallow or speak. Some people with Sjogren's syndrome also have one or more of the following Joint pain, swelling and stiffness Sjogren's syndrome - Symptoms and causes - Mayo Clinic. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil Side Effects Common, Severe, Long Term -. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. We study how severe was Dry mouth, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil from sources other than FDA, and is updated regularly. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.